Nucleophilic Addition To A Carbonyl

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Slide 21 of 49

Notes:

Transp 16-5 Leaving Group Ability

If nucleophile is weak:

R-C=O + H+ ----> R-C+-O-H

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L L

Nuc

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R-C+-O-H + Nuc - -----> R-C-O-H

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L L